Marlins @ Padres

Who will WIN this matchup?

Miami Marlins (47-67)

@ San Diego Padres (66-49)

Starting Pitchers:

Alcantara (MIA): 6-10; 3.70 ERA

Weathers (SD) 4-4; 4.26 ERA

Current odds:

Miami Marlins: (+145)

San Diego Padres: (-155)

• Rookie left-hander Ryan Weathers, who pitched four scoreless innings against the Miami Marlins last month, hopes to lead the Padres to a three-game sweep on Wednesday afternoon in San Diego. San Diego beat Miami 6-5 on Tuesday, marking the Padres’ fourth straight win and the Marlins’ fifth consecutive defeat. Weathers (4-4, 4.26 ERA) held Miami to just two hits on July 24, but he left with a no-decision after four innings. The Padres are 9-11 when Weathers pitches, and he hasn’t earned a win since July 6.

• The Marlins will start right-hander Sandy Alcantara (6-10, 3.70 ERA), who has never faced the Padres.

• There’s a good chance the Marlins will start rookie catcher Alex Jackson, who is a San Diego native.

• Meanwhile, with San Diego star shortstop Fernando Tatis Jr. out due to a shoulder injury, first baseman Eric Hosmer has stepped up for the Padres. Since July 1, Hosmer is hitting .426 at Petco Park — the highest home batting average in the majors during that span (minimum 50 plate appearances). Tatis is eligible to return to the lineup on Wednesday, but Padres manager Jayce Tingler said that will not happen.

• Even without Tatis, the Padres bounced back from a 3-0 deficit on Tuesday. Four San Diego players — Hosmer, Austin Nola, Wil Myers and Trent Grisham — had two hits. Myers also walked twice.

• The Padres, though, had to use eight pitchers and likely will have a tired bullpen for Wednesday’s game. In addition, reliever Drew Pomeranz left the Tuesday contest because of forearm tightness. His status for Wednesday was unclear.

• All of that puts pressure on Weathers, who has yet to go past 5 2/3 innings this season.

• Miami is in slightly better shape in terms of its pitching staff, and that’s partly because the Marlins used just six pitchers on Tuesday. In addition, Alcantara has shown a strong tendency to give the Marlins length. He has lasted at least six innings on 17 occasions this year. He has lasted at least seven innings in seven games.

• Unfortunately for the Marlins, they are 11-23 in one-run games, and they took another hit in that regard on Tuesday.

• One way the Marlins are trying to find an edge is by running more. Since the start of July, the Marlins lead the majors with 28 steals. The Marlins have some fast players, including Magneuris Sierra, who has stolen six bases and has not been caught, and Jazz Chisholm Jr., who is on the injured list.