Titans @ Colts

Who will WIN this matchup?

Tennessee Titans (7-3)

@ Indianapolis Colts (7-3)

Current odds:

Tennessee Titans: (+140)

Indianapolis Colts: (-160)

• The line for this game is Colts by 3 points.

• The AFC South division lead and a distinct edge in the playoff race will be at stake Sunday when the Tennessee Titans visit the Indianapolis Colts. Both teams enter at 7-3 after victories last week. The Titans won 30-24 at Baltimore, and the host Colts defeated Green Bay 34-31. Both games went to overtime. A loss at Lucas Oil Stadium this week could be very costly in the AFC playoff race, as current wild-card hopefuls Miami (6-4), Cleveland (7-3) and Las Vegas (6-4) all are favored heading into their road games.

• Indianapolis already defeated Tennessee on Nov. 12 in Nashville, Tenn., when the Colts used a 21-point second half to prevail 34-17. A win Sunday would give the Colts a one-game lead in the division and the all-important tiebreaker between the teams.

• Tannehill was 15 of 27 for 147 yards and a touchdown in the first meeting, when Tennessee was outgained 430-294 overall and neither team ran the ball incredibly well.

• NFL leading rusher Derrick Henry (1,079 yards, 4.7 avg.) leads a Titans rushing attack ranked fifth in the league. The Colts’ defense, however, is ranked second overall (298.1 ypg.) and third against the run, allowing 89.2 yards per game.

• Philip Rivers directs Indy’s offense, which has outscored its last two opponents 41-3 in the second half/overtime. Rivers, in his first season with the Colts after 16 seasons with the San Diego/Los Angeles Chargers, did not practice Wednesday due to a toe injury suffered against Green Bay. Coach Frank Reich said he expected that another off day on Thanksgiving would enable Rivers to make his 235th consecutive regular season start. Rivers completed 29 of 39 for 308 yards and a TD against Tennessee in Round 1.

• Titans punter Brett Kern is expected to return after missing three games due to a wrist injury. In the teams’ first meeting, a shanked punt by Trevor Daniel and a blocked punt that resulted in a touchdown cost Tennessee greatly.

• Tennessee receiver Adam Humphries, who missed the last three games with a concussion, has been ruled out Sunday’s contest. He joins cornerback Adoree Jackson (knee) and tight end MyCole Pruitt (knee) in being ruled out for this game.

• On Saturday, Colts rookie running back Jonathan Taylor was added to the reserve/COVID-19 list and ruled out against the Titans. The team also downgraded center Ryan Kelly (neck) to out and cornerback Isaiah Rodgers (knee) to questionable. Taylor leads the team in carries (135), rushing yards (518) and rushing touchdowns (four). He also has 26 catches for 227 yards in 10 games this season for Indianapolis. Fellow running backs Jordan Wilkins and Nyheim Hines are expected to handle the rushing duties.